Even now, numerous missing children and their guardians(family) are desperately looking for each other. It is a natural responsibility of the state to make efforts in various ways at the pan-governmental level for their reunion. So far, there are 30,275 missing children registered and managed in the missing children DNA database, and there are 3,232 guardians, which is about 10 times the number of guardians (as of April 11, 2023). Until now, about 630 cases of family reunion have been made directly or indirectly through the missing children DNA database. Some of the main cases are reported in this study.